Map3k8 Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comMap3k8 Polyclonal Antibody for Rat(Rattus norvegicus)

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Map3k8 (Gene name),

Mitogen-activated protein kinase kinase kinase 8 (Protein name ), M3K8_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Map3k8(Tpl2);

Protein name:

Mitogen-activated protein kinase kinase kinase 8;

Alternative:

Tumor progression locus 2(TPL-2);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Forms a ternary complex with NFKB1 and TNIP2.

Function:

Required for TLR4 activation of the MEK/ERK pathway. Able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105. Plays a role in the cell cycle.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

467

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

467:

LAGYFNIVRG | PPTLEYG

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:116596

STRING:

10116.ENSRNOP00000022190

String:

Q63562

UniGene:

Rn.9939

Pfam:

PF00069

Uniprot:

Q63562

FOR

ELISA Kit for Rat Mitogen-activated protein kinase kinase kinase 8

Cat.:

E10350h

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Rat Mitogen-activated protein kinase kinase kinase 8

Cat.:

E10350m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Rat Mitogen-activated protein kinase kinase kinase 8

Cat.:

E10350r

Price:

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Packing:

96T

CLIA Kit for Rat Mitogen-activated protein kinase kinase kinase 8

Cat.:

U10350h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat Mitogen-activated protein kinase kinase kinase 8

Cat.:

U10350m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Mitogen-activated protein kinase kinase kinase 8

Cat.:

U10350r

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 8

Cat.:

P10350Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 8

Cat.:

P10350Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 8

Cat.:

P10350Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 8

Protein for Rat Mitogen-activated protein kinase kinase kinase 8

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation."
Patriotis C. , Makris A. , Bear S.E. , Tsichlis P.N.
Proc. Natl. Acad. Sci. U.S.A.90:2251-2255(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
strain: Long Evans.
tissue: Liver.
2.

"TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105."
Belich M.P. , Salmeron A. , Johnston L.H. , Ley S.C.
Nature397:363-368(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NFKB1

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